Small Molecule Drug Discovery
Biovaya applies structure-based design and AI-driven target identification to discover transformative small molecule therapeutics for unmet medical needs.
How We Work
An integrated, iterative pipeline from validated biology to development-ready candidates.
Target Identification
Multi-omics integration and human genetics to identify high-confidence, genetically-validated targets with clear disease linkage.
Lead Discovery & Optimization
Fragment-based screening, virtual docking, and AI-guided medicinal chemistry optimization across the hit-to-lead cascade.
Candidate Selection
In vitro and in vivo ADMET profiling, selectivity panels, and IND-enabling toxicology studies to nominate development candidates.
Development Portfolio
Three programs advancing across autoimmune, oncology, and inflammatory disease indications.
| Program | Target | Indication | Stage |
|---|---|---|---|
| BVY-101 | DHODH | Autoimmune Disease | IND-Enabling |
| BVY-202 | BRD4 (Degrader) | Oncology | Lead Optimization |
| BVY-303 | NLRP3 | Inflammatory Disease | Hit Identification |
Infrastructure
Deep expertise across structural biology, computation, and translational pharmacology.
Structural Biology
Cryo-EM structure determination and X-ray crystallography for structure-based drug design at atomic resolution.
Computational Chemistry
FEP+, AIMD, and ML-guided design for rapid lead optimization cycles with predictive accuracy at scale.
ADMET Modeling
In silico and in vitro ADMET prediction integrated into design workflows from day one to reduce attrition.
Science
Peer-reviewed research underpinning our discovery programs.
Leadership
Rooted in deep science and translational pharmaceutical experience.
Founder & Chief Scientific Officer
Our founder holds a PhD in Medicinal Chemistry from UCSF and completed postdoctoral research at the Broad Institute of MIT and Harvard. She has 12 years of pharmaceutical R&D experience and is an inventor on 8 issued patents in kinase biology and targeted protein degradation.
We welcome inquiries from potential partners, investors, and collaborators advancing small molecule therapeutics.
Get in touch
Location
Cambridge, MA 02139Facility
Kendall Square Innovation LabMeetings
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